SynBioSS (Synthetic Biology Software Suite) is a suite of software for the modeling and simulation of synthetic genetic constructs. SynBioSS utilizes the registry of standard biological parts, a database of kinetic parameters, and both graphical and command-line interfaces to multiscale simulation algorithms. SynBioSS is available under the GNU General Public License. — Anthony D. Hill, Jonathan R. Tomshine, Emma M. B. Weeding, Vassilios Sotiropoulos, and Yiannis N. Kaznessis, Bioinformatics 2008 24(21):2551-2553; doi:10.1093/bioinformatics/btn468

Sounds neat, let’s try it. Interestingly, the iGEM participants and biologists, in discussions of modeling, have thrown their hands in the air & state that it is difficult or impossible to model biology. Maybe SynBioSS can do the impossible?  Except: There is no specific installer available for OS/X (as of this writing) and it seems there are many assorted packages required.

Here are my install summary/notes/fixes for getting SynBioSS (version 1.0.1) running on OS/X (Leopard 10.5.5):
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