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	Comments on: Skunkworks Bioengineering &#8212; Prerequisites to Success?	</title>
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	<link>http://88proof.com/synthetic_biology/blog/archives/174</link>
	<description>Genetically Engineered Organisms, Systems Biology, and Synthetic Biology from an Engineer&#039;s Viewpoint</description>
	<lastBuildDate>Fri, 07 May 2010 01:12:26 +0000</lastBuildDate>
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		<title>
		By: Matt		</title>
		<link>http://88proof.com/synthetic_biology/blog/archives/174/comment-page-1#comment-109</link>

		<dc:creator><![CDATA[Matt]]></dc:creator>
		<pubDate>Fri, 07 May 2010 01:12:26 +0000</pubDate>
		<guid isPermaLink="false">http://88proof.com/synthetic_biology/blog/?p=174#comment-109</guid>

					<description><![CDATA[Jonathan,

I am curious what you are actually trying to do... You list is far too general for one thing. Is there a particular project that you are building up to...?]]></description>
			<content:encoded><![CDATA[<p>Jonathan,</p>
<p>I am curious what you are actually trying to do&#8230; You list is far too general for one thing. Is there a particular project that you are building up to&#8230;?</p>
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		<title>
		By: Jonathan Cline		</title>
		<link>http://88proof.com/synthetic_biology/blog/archives/174/comment-page-1#comment-37</link>

		<dc:creator><![CDATA[Jonathan Cline]]></dc:creator>
		<pubDate>Tue, 18 Nov 2008 05:03:06 +0000</pubDate>
		<guid isPermaLink="false">http://88proof.com/synthetic_biology/blog/?p=174#comment-37</guid>

					<description><![CDATA[Yes - motivation is always #1.  Basically most pro&#039;s in the field currently mirror that comment:  &quot;no formal biology training .. picked it up on the way.&quot;

Recently found this web presentation, linked from UCB iGEM 2008 team wiki.

&quot;What Foundational Knowledge is Required for Scientific Inquiry in Synthetic Biology?&quot;
--  http://www.vuvox.com/collage/detail/0a23ffbf4

The conclusion was that basically anyone who finishes the typical Bio1A class is ready to go.

The following link at the Anderson Lab tutorials gives the &quot;bare bones&quot; background tutorials  -- http://andersonlab.qb3.berkeley.edu/Tutorials/iGEMTutorial.html

The rapidly reducing cost of experimentation is the exciting part.  Iterating over many experiments is fine, it&#039;s how man built airplanes and learned to fly-- as long as the cost of each experiment isn&#039;t prohibitive, trial &#038; error prototyping allows rapid progress to be made through trial &#038; error.   In computer science, the current trendy term for this is &quot;extreme programming (XP)&quot; or &quot;agile development&quot;.  In computer science, this works great, because the cost of each experiment ($$$) is basically zero.]]></description>
			<content:encoded><![CDATA[<p>Yes &#8211; motivation is always #1.  Basically most pro&#8217;s in the field currently mirror that comment:  &#8220;no formal biology training .. picked it up on the way.&#8221;</p>
<p>Recently found this web presentation, linked from UCB iGEM 2008 team wiki.</p>
<p>&#8220;What Foundational Knowledge is Required for Scientific Inquiry in Synthetic Biology?&#8221;<br />
&#8212;  <a href="http://www.vuvox.com/collage/detail/0a23ffbf4" rel="nofollow ugc">http://www.vuvox.com/collage/detail/0a23ffbf4</a></p>
<p>The conclusion was that basically anyone who finishes the typical Bio1A class is ready to go.</p>
<p>The following link at the Anderson Lab tutorials gives the &#8220;bare bones&#8221; background tutorials  &#8212; <a href="http://andersonlab.qb3.berkeley.edu/Tutorials/iGEMTutorial.html" rel="nofollow ugc">http://andersonlab.qb3.berkeley.edu/Tutorials/iGEMTutorial.html</a></p>
<p>The rapidly reducing cost of experimentation is the exciting part.  Iterating over many experiments is fine, it&#8217;s how man built airplanes and learned to fly&#8211; as long as the cost of each experiment isn&#8217;t prohibitive, trial &amp; error prototyping allows rapid progress to be made through trial &amp; error.   In computer science, the current trendy term for this is &#8220;extreme programming (XP)&#8221; or &#8220;agile development&#8221;.  In computer science, this works great, because the cost of each experiment ($$$) is basically zero.</p>
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		<title>
		By: Rob Carlson		</title>
		<link>http://88proof.com/synthetic_biology/blog/archives/174/comment-page-1#comment-36</link>

		<dc:creator><![CDATA[Rob Carlson]]></dc:creator>
		<pubDate>Thu, 13 Nov 2008 17:48:18 +0000</pubDate>
		<guid isPermaLink="false">http://88proof.com/synthetic_biology/blog/?p=174#comment-36</guid>

					<description><![CDATA[Biology may be hard, but frankly for many people so are physics and basic circuit design and analysis (having taught these courses many times over the years).  And I have watched many people who fare poorly at basic physics and engineering excel at the wet bench.  Dunno why that is, but it seems to work both ways.  Many physics and engineering students just flail around in biology classes.

I don&#039;t have any formal biology training -- no laboratory courses -- and everything I know how to do at the bench I picked up by watching somebody else or by reading a recipe.

What it *really* takes is just a willingness to try anything, and to put up with failure.

- Rob]]></description>
			<content:encoded><![CDATA[<p>Biology may be hard, but frankly for many people so are physics and basic circuit design and analysis (having taught these courses many times over the years).  And I have watched many people who fare poorly at basic physics and engineering excel at the wet bench.  Dunno why that is, but it seems to work both ways.  Many physics and engineering students just flail around in biology classes.</p>
<p>I don&#8217;t have any formal biology training &#8212; no laboratory courses &#8212; and everything I know how to do at the bench I picked up by watching somebody else or by reading a recipe.</p>
<p>What it *really* takes is just a willingness to try anything, and to put up with failure.</p>
<p>&#8211; Rob</p>
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